I’m sure this has happened before to many people. And I’m sure it will happen again.
For some reason, explorer blocks in your RDP session, and you want to open task manager, and you can’t do Ctrl + Alt+ Del because it will open the computers Task Manager menu and not the RDP session menu. So how do you get there? Simple. Microsoft has another keyboard shortcut for that. Just press Ctrl + Alt + End and that’s it.